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CNS depressants are the correct class of prescription drugs used to treat anxiety. This category primarily includes benzodiazepines and certain antidepressants, which help to calm the nervous system and reduce anxiety symptoms. By enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA), CNS depressants produce a calming effect that can alleviate anxiety and promote relaxation.

Opioids are primarily prescribed for pain management and can lead to dependence and addiction, making them inappropriate for treating anxiety. Stimulants, on the other hand, are typically utilized to treat attention deficit hyperactivity disorder (ADHD) and can actually exacerbate anxiety due to their stimulating effects. Hallucinogens are substances that alter perception, mood, and cognitive processes but do not have a therapeutic role in the treatment of anxiety disorders.

Thus, CNS depressants remain the preferred choice for the management of anxiety-related conditions due to their efficacy in promoting relaxation and reducing anxious feelings.